quote:De politie van Madeira Beach in de Amerikaanse staat Florida heeft maandag een 41-jarige man gearresteerd. De man simuleerde telkens dat hij bezig was te verdrinken. Vervolgens begon Keith Edward Marriott met kwallen te gooien naar pubers die bij hem in de buurt dreigden te komen.
quote:SA pigeon 'faster than broadband'
Broadband promised to unite the world with super-fast data delivery - but in South Africa it seems the web is still no faster than a humble pigeon.
A Durban IT company pitted an 11-month-old bird armed with a 4GB memory stick against the ADSL service from the country's biggest web firm, Telkom. Winston the pigeon took two hours to carry the data 60 miles - in the same time the ADSL had sent 4% of the data.
Telkom said it was not responsible for the firm's slow internet speeds.
The idea for the race came when a member of staff at Unlimited IT complained about the speed of data transmission on ADSL. He said it would be faster by carrier pigeon. "We renown ourselves on being innovative, so we decided to test that statement," Unlimited's Kevin Rolfe told the Beeld newspaper.
...
quote:Het idee dat de vrouw ook aan seks doet en er zelfs van geniet, is te schokkend voor de gekke Japanners.
Bij een bestandje van 100kb een keer of 10 heen en weer zenden ligt dat dan net weer iets anders.quote:
Och, je hebt wel een paar terrabyte binnen in een paar uur als je zo'n duif volhangt met usbstickies.quote:Op donderdag 10 september 2009 19:20 schreef Monolith het volgende:
[..]
Bij een bestandje van 100kb een keer of 10 heen en weer zenden ligt dat dan net weer iets anders.
Hoe zouden torrents op basis van postduiven werken?quote:Op donderdag 10 september 2009 19:37 schreef Boze_Appel het volgende:
[..]
Och, je hebt wel een paar terrabyte binnen in een paar uur als je zo'n duif volhangt met usbstickies.
quote:Op donderdag 10 september 2009 21:15 schreef Monolith het volgende:
Hoe zouden torrents op basis van postduiven werken?
Zo vind ik uw zinspeling op Harderwijk nog steeds ondoorgrondelijk.quote:Op donderdag 10 september 2009 21:35 schreef Reya het volgende:
Uw scherpzinnigheid gaat me te boven.
Ik mis haar wel, wakker worden van het luiden van de haar klokken had toch wel wat, hoog tijd om weer een keer naar Stad te gaanquote:Op donderdag 10 september 2009 19:10 schreef sigme het volgende:
d' Olle Grieze.
De Universiteit van Harderwijk! Klokhuis jeweetwel!quote:Op donderdag 10 september 2009 21:37 schreef TitusPullo het volgende:
[..]
Zo vind ik uw zinspeling op Harderwijk nog steeds ondoorgrondelijk.
quote:"Harderwijk is een stad van negotie,
Men verkoopt er bokking, blauwbessen en bullen van promotie."
Ik denk dat Reya op het volgende doelde:quote:Op donderdag 10 september 2009 22:13 schreef TitusPullo het volgende:
Ja, maar het is mij onduidelijk door middel van welke associatie hij EchtGaaf aan dat instituut verbond.
quote:Over iemand die enigszins dom overkomt wordt ook wel gezegd dat hij 'van de Universiteit van Harderwijk' komt.
Nuance is als olie op de golven.quote:Op donderdag 10 september 2009 22:38 schreef TitusPullo het volgende:
Dat vind ik bepaald schaamteloos.
Wat is het dat je aantrekt?quote:Op donderdag 10 september 2009 22:45 schreef TitusPullo het volgende:
Jullie mogen best weten dat ik van het najaar houd.
Ich habe es nicht gewusst!quote:Op donderdag 10 september 2009 22:56 schreef TitusPullo het volgende:
En natuurlijk gedenk ik dan het feit dat ik alweer geen POL-vergadering bezocht, en dat ik meerdere blogs schreef over de erfenis van de babyboomers, met instemmende reacties van jongeren en vaak boze, ontkennende reacties van babyboomers.
Ik kan enkel met u instemmen, maar primair om de meer prozaïsche reden dat ondergetekende zomerhitte bijzonder slecht tolereert.quote:Op donderdag 10 september 2009 22:45 schreef TitusPullo het volgende:
Jullie mogen best weten dat ik van het najaar houd.
quote:Rep. Joe Wilson's (R-S.C.) untoward outburst Wednesday night has had a positive effect for at least one person. Rob Miller, a Democrat planning to run against Wilson in 2010, has taken in more than $350,000 from over 5,000 people through the website ActBlue.com since his opponent heckled the president.
A sizable chunk of the money has come from Daily Kos readers through a group called "Defeating the man who yelled 'liar' at Obama."
quote:Please give us all your money
How do patents affect science? This week in India, US drug company Gilead lost their appeal to stop local companies making cheap copies of their Aids drug Tenofovir. They are not alone: in 2007 Novartis lost a lengthy case trying to force the Indian government into strengthening their weak patent laws. India remains the free pharmacy of the world.
Cheap drugs may not be the only benefit of India’s approach, but the drugs are certainly cheap. The cost of Tenofovir in developed countries is $5,700 per patient per year: the Indian generic version is available in the developing world for just $800. Because of this price difference, 75% of the 4m people in the world taking medication for Aids are using generic copies. Almost all of these are made in India, and in fact, about 40% of the world’s aids patients are taking drugs made by one company: Cipla, which is now the biggest manufacturer of antiretroviral drugs in the world.
Ignoring patent and licensing issues has allowed Dr Yusuf Hamied, director of Cipla, to innovate: even though each drug is officially owned by a different company, he could put a common combination of three treatments (Stavudine, Lamivudine and Nevirapine) into one simple, single combination pill. This increases treatment compliance – it’s easier to take your medication correctly – and that keeps you alive longer, while reducing the emergence of resistant strains.
Hamied calls his pill Triomune (he also offers “Antiflu”, a copy of Tamiflu for the developing world, and many more). In 2001 he was selling to MSF clinics for $350 per person per year, more than 30 times cheaper than the official versions of these drugs. Triomune is now only $87 a year. This is amazing. Hamied is a hero.
Richard Sykes, head of GlaxoSmithKline (and now now retired rector of Imperial College London) disagreed. He called Hamied a “pirate” and described the quality of Indian generic drugs as “iffy”. Hamied says GSK is a “global serial killer“ for charging high prices for their medication. So who is right?
Drug patents are a fascinating trade off between the benefit of incentive, and the harm to innovation. It takes about $800m and 10 years to bring a drug to market: during this time you make no money, and your drug could fail at any stage. As a sweetener, after this, you have 10 years of being the sole manufacturer to recoup your costs and make a profit.
There are other benefits for all of us. Instead of relying on obsessive secrecy to protect your idea (which is how Coca Cola protect their recipe) patents allow drug companies to safely disclose more information in public, which helps other people innovate. Protecting ideas also allows a smaller company negotiate outside investment and develop their theories.
But patents can also retard innovation. Even though your competitors may have greater expertise in the relevant fields, they will be hindered from doing research into derivatives of your drug, or other uses for it, or improvements to it. Thomas Edison managed to get a broad patent on his improvements to the light bulb, and this forced his competitors – who had made subsequent technical improvements of their own – out of business. It took a World War to cajole the Wright brothers into finally agreeing licenses for everyone else over their patent on the airplane.
And the other downside, of course, is the monopoly. With patents you are the sole provider of a drug, you get to set the price in each country, and if your drug is lifesaving then everyone has to pay it, or die. In lots of places, they just die. There are 33 million people living with Aids in the world today. 2 million die every year, and at the moment, despite heroic improvements over the last 5 years, 70% of those who need treatment do not get it.
Patents weren’t devised out of a sense of natural justice. They are there to incentivise innovation, to “add the fuel of interest to the fire of genius”, as Abraham Lincoln said. So how much fuel can you get from the developing world? According to MSF, Africa, for example, accounts for a non-massive 1% of the world’s medicine market.
If the global $550bn pharmaceutical industry are trying to make an economic case for patents in the developing world, then they must argue that the benefit to drug development from the financial incentives in these tiny corners of the world market is so significant – so vital, the final link in the incentive chain – that it is more important than millions of unnecessary deaths. I am not a health economist, but I doubt that is a fair swap, and this is not what patent laws were invented for.
quote:Question
My wife won't stop complaining?
I am a really upbeat person and I always look for the positive in things but my wife is the complete opposite. It seems she only looks for something to complain about. She doesnt look for the beautiful in the world, only the ugly and it is driving me crazy. She has been this way pretty much her whole life I've been told and I was wondering if anybody had any ideas on how to reach my wife so she doesn't complain about every little thing. Just once I would like her to go a whole day being happy and carefree. Any suggestions (please no sarcastic answers)?
quote:Best Answer
I live a mom who is just like that. But in your case, I would have to say she must of been abused growing up. She must of had some kind of trauma happen to her that she just doesn't like the world that should of been safe for her while growing up.
I would ask her questions about her childhood. Like has anyone ever touched you in the wrong places and if so was this person someone you once trusted?
Also, ask her to be put on medicine. I take Effexxor..Great anxiety depression pills.
moet de titel aangepast wordenquote:Op donderdag 10 september 2009 16:46 schreef Nautilus_ het volgende:
Och gunst, dit is natuurlijk deel 1579.
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