Vitamine D3 en het Corona-virus

Vitamin D is better than ANY vaccine and increases the immune system by 3-5 times

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Op maandag 8 maart 2021 21:43 schreef Wantie het volgende:

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Dat gaat over griep.

En ook over het immuunsysteem.

High vitamin D levels may protect against COVID-19, especially for Black people

A new research study at the University of Chicago Medicine has found that when it comes to COVID-19, having vitamin D levels above those traditionally considered sufficient may lower the risk of infection, especially for Black people.

The study, published March 19 in JAMA Open Network, retrospectively examined the relationship between vitamin D levels and likelihood of testing positive for COVID-19. While levels of 30 ng/ml or more are usually considered "sufficient," the authors found that Black individuals who had levels of 30 to 40 ng/ml had a 2.64 times higher risk of testing positive for COVID-19 than people with levels of 40 ng/ml or greater. Statistically significant associations of vitamin D levels with COVID-19 risk were not found in white people. The study looked at data from over 3,000 patients at UChicago Medicine who had had their vitamin D levels tested within 14 days before a COVID-19 test.

The research team is now recruiting participants for two separate clinical trials testing the efficacy of vitamin D supplements for preventing COVID-19.

This research is an expansion of an earlier study showing that a vitamin D deficiency (less than 20 ng/ml) may raise the risk of testing positive for COVID-19. In the current study, those results were further supported, finding that individuals with a vitamin D deficiency had a 7.2% chance of testing positive for the virus. A separate study recently found that over 80% of patients diagnosed with COVID-19 were vitamin D deficient.

Gaat verder:

https://www.eurekalert.or(...)3/uocm-hvd031721.php

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Op maandag 22 maart 2021 17:11 schreef Gehrman het volgende:

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Antivaxxer propaganda. Tuurlijk is vitamine d goed maar beweren dat het beter is dan vaccinatie is regelrechte nonsens.

Misschien moet je luisteren naar de dokter in de video en het onderzoek dat besproken wordt. Je maakt je nu druk om de titel van een youtube filmpje die gekozen is door een willekeurige youtuber.

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Op maandag 22 maart 2021 18:33 schreef Wantie het volgende:

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Dat vitamine D goed is voor je immuunsysteem staat niet ter discussie.
Maar wat de dokter zoal beweert in die video gaat wel over de rand.
Wat griep vaccins betreft: die is naar verluid maar 50-60% effectief, dus goed op je vitamine D letten zou wel eens meer effect kunnen hebben.
Maar beweren dat elke ziekte waar vaccins voor zijn beter te voorkomen zijn met vitamine D is een brug te ver.

Dat zegt hij geen eens. Hij praat over een studie naar de vogelgriep uit 1921 en de Duitse wetenschappers die de studie deden dachten dat Vitamine D een betere oplossing zou zijn dan een vaccin. Deze uitspraak wordt dus gedaan in de context van de vogelgriep in 1921.

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Op maandag 22 maart 2021 18:53 schreef Wantie het volgende:

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Vitamin D is better than ANY vaccine and increases the immune system by 3-5 times

Staat er toch echt..

Zoals ik zojuist bij een andere user ook al aangaf: je moet wel de video kijken en luisteren naar de dokter. Lekker belangrijk dat een willekeurige youtuber een ongenuanceerde titel kiest voor de video.

edit: toegegeven, ik was wat snel met het kopieren / plakken van de video in mijn post en had zelf daar wat nuance bij moeten plaatsen.

[ Bericht 8% gewijzigd door Probably_on_pcp op 22-03-2021 19:05:40 ]

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Op maandag 22 maart 2021 19:09 schreef Wantie het volgende:

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Het citaat komt uit de video zelf, en de beste man beweert ook dat een terminale patiënt met longkanker genezen is met vitamine D.
Het is allemaal nogal controversieel wat hij beweert.

Het citaat komt uit de video zelf en werd gedaan in een bepaalde context, nl. door Duitse wetenschappers in 1921 die met de vogelgriep bezig waren.

En hij deelt in inderdaad een anekdote over een patiënt die zegt genezen te zijn door Vitamine D. De dokter zegt niet dat iedereen met longkanker de reguliere behandeling moet stop zetten en Vitamine D moet gaan slikken. Zo controversieel is hij dus niet.

Over 200 Scientists & Doctors Call For Increased Vitamin D Use To Combat COVID-19
Scientific evidence indicates vitamin D reduces infections & deaths

To all governments, public health officials, doctors, and healthcare workers,

[Residents of the USA: Text “VitaminDforAll” to 50409 to send this to your state’s governor.]

Research shows low vitamin D levels almost certainly promote COVID-19 infections, hospitalizations, and deaths. Given its safety, we call for immediate widespread increased vitamin D intakes.

Vitamin D modulates thousands of genes and many aspects of immune function, both innate and adaptive. The scientific evidence1 shows that:

Higher vitamin D blood levels are associated with lower rates of SARS-CoV-2 infection.
Higher D levels are associated with lower risk of a severe case (hospitalization, ICU, or death).
Intervention studies (including RCTs) indicate that vitamin D can be a very effective treatment.
Many papers reveal several biological mechanisms by which vitamin D influences COVID-19.
Causal inference modelling, Hill’s criteria, the intervention studies & the biological mechanisms indicate that vitamin D’s influence on COVID-19 is very likely causal, not just correlation.

Vitamin D is well known to be essential, but most people do not get enough. Two common definitions of inadequacy are deficiency < 20ng/ml (50nmol/L), the target of most governmental organizations, and insufficiency < 30ng/ml (75nmol/L), the target of several medical societies & experts.2 Too many people have levels below these targets. Rates of vitamin D deficiency <20ng/ml exceed 33% of the population in most of the world, and most estimates of insufficiency <30ng/ml are well over 50% (but much higher in many countries).3 Rates are even higher in winter, and several groups have notably worse deficiency: the overweight, those with dark skin (especially far from the equator), and care home residents. These same groups face increased COVID-19 risk.

It has been shown that 3875 IU (97mcg) daily is required for 97.5% of people to reach 20ng/ml, and 6200 IU (155mcg) for 30ng/ml,4 intakes far above all national guidelines. Unfortunately, the report that set the US RDA included an admitted statistical error in which required intake was calculated to be ~10x too low.4 Numerous calls in the academic literature to raise official recommended intakes had not yet resulted in increases by the time SARS-CoV-2 arrived. Now, many papers indicate that vitamin D affects COVID-19 more strongly than most other health conditions, with increased risk at levels < 30ng/ml (75nmol/L) and severely greater risk < 20ng/ml (50nmol/L).1

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1 The evidence was comprehensively reviewed (188 papers) through mid-June [Benskin ‘20] & more recent publications are increasingly compelling [Merzon et al ‘20; Kaufman et al ‘20; Castillo et al ‘20]. (See also [Jungreis & Kellis ‘20] for deeper analysis of Castillo et al’s RCT results.)

2 E.g.: 20ng/ml: National Academy of Medicine (US, Canada), European Food Safety Authority, Germany, Austria, Switzerland, Nordic Countries, Australia, New Zealand, & consensus of 11 international organizations. 30ng/ml: Endocrine Society, American Geriatrics Soc., & consensus of scientific experts. See also [Bouillon ‘17].

3 [Palacios & Gonzalez ‘14; Cashman et al ‘16; van Schoor & Lips ‘17] Applies to China, India, Europe, US, etc.

4 [Heaney et al ‘15; Veugelers & Ekwaru ‘14]

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Evidence to date suggests the possibility that the COVID-19 pandemic sustains itself in large part through infection of those with low vitamin D, and that deaths are concentrated largely in those with deficiency. The mere possibility that this is so should compel urgent gathering of more vitamin D data. Even without more data, the preponderance of evidence indicates that increased vitamin D would help reduce infections, hospitalizations, ICU admissions, & deaths.

Decades of safety data show that vitamin D has very low risk: Toxicity would be extremely rare with the recommendations here. The risk of insufficient levels far outweighs any risk from levels that seem to provide most of the protection against COVID-19, and this is notably different from drugs. Vitamin D is much safer than steroids, such as dexamethasone, the most widely accepted treatment to have also demonstrated a large COVID-19 benefit. Vitamin D’s safety is more like that of face masks. There is no need to wait for further clinical trials to increase use of something so safe, especially when remedying high rates of deficiency/insufficiency should already be a priority.

Therefore, we call on all governments, doctors, and healthcare workers worldwide to immediately recommend and implement efforts appropriate to their adult populations to increase vitamin D, at least until the end of the pandemic. Specifically to:

Recommend amounts from all sources sufficient to achieve 25(OH)D serum levels over 30ng/ml (75nmol/L), a widely endorsed minimum with evidence of reduced COVID-19 risk.
Recommend to adults vitamin D intake of 4000 IU (100mcg) daily (or at least 2000 IU) in the absence of testing. 4000 IU is widely regarded as safe.5
Recommend that adults at increased risk of deficiency due to excess weight, dark skin, or living in care homes may need higher intakes (eg, 2x). Testing can help to avoid levels too low or high.
Recommend that adults not already receiving the above amounts get 10,000 IU (250mcg) daily for 2-3 weeks (or until achieving 30ng/ml if testing), followed by the daily amount above. This practice is widely regarded as safe. The body can synthesize more than this from sunlight under the right conditions (e.g., a summer day at the beach). Also, the NAM (US) and EFSA (Europe) both label this a “No Observed Adverse Effect Level” even as a daily maintenance intake.
Measure 25(OH)D levels of all hospitalized COVID-19 patients & treat with calcifediol or D3, to at least remedy insufficiency <30ng/ml (75nmol/L), possibly with a protocol along the lines of Castillo et al ‘20 or Rastogi et al '20, until evidence supports a better protocol.

Many factors are known to predispose individuals to higher risk from exposure to SARS-CoV-2, such as age, being male, comorbidities, etc., but inadequate vitamin D is by far the most easily and quickly modifiable risk factor with abundant evidence to support a large effect. Vitamin D is inexpensive and has negligible risk compared to the considerable risk of COVID-19.

Please Act Immediately

https://vitamind4all.org/letter.html