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pi_199926978
quote:
0s.gif Op donderdag 17 juni 2021 14:34 schreef Za het volgende:

[..]

Dat geldt toch ook voor niet gevaccineerden?
Het aantal besmettingen lag in januari op 70.000 per dag vs 2000 in mei, volgens BJ ten gevolge van de lockdown.

Inmiddels raken steeds meer gevaccineerden besmet, en vertegenwoordigen zij dagelijks meer dan een derde van de ziekenhuisopnames.

Gisteren ruim 9000 besmettingen in de UK, de verwachting is rond de 60.000 juli/aug.
Meer dan een derde van de ziekenhuisopnames van mensen die gevaccineerd zijn? Dat is nogal veel.

Zijn die mensen volledig gevaccineerd of hebben ze alleen een enkele gehad?
  donderdag 17 juni 2021 @ 14:37:58 #122
94451 SillyWalks
Ministry of Silly Walks
pi_199927008
quote:
0s.gif Op donderdag 17 juni 2021 14:11 schreef Arcee het volgende:

[..]

Het ging over mijnrivm, die het doorgestuurd krijgen van de GGD en dat boeit dan dus niet.
Als je door de GGD geprikt bent, en het staat niet bij de GGD in het systeem, dan zal het ook nooit goed gaan staan bij RIVM.

Daarom afwachten tot GGD z'n zaakjes op orde heeft.
Minister: lt's not particularly silly, is it? I mean, the right leg isn't silly at all and the left leg merely does a forward aerial half turn every alternate step.
Mr Pudey: Yes, but I think that with Government backing I could make it very silly.
pi_199927024
quote:
0s.gif Op donderdag 17 juni 2021 14:36 schreef chratnox het volgende:

[..]

Meer dan een derde van de ziekenhuisopnames van mensen die gevaccineerd zijn? Dat is nogal veel.

Zijn die mensen volledig gevaccineerd of hebben ze alleen een enkele gehad?
Merendeel enkele
  donderdag 17 juni 2021 @ 14:39:45 #124
38559 WheeledWarrior
More than meets the eye
pi_199927038
quote:
0s.gif Op donderdag 17 juni 2021 14:34 schreef Za het volgende:

[..]

Dat geldt toch ook voor niet gevaccineerden?
Het aantal besmettingen lag in januari op 70.000 per dag vs 2000 in mei, volgens BJ ten gevolge van de lockdown.

Inmiddels raken steeds meer gevaccineerden besmet, en vertegenwoordigen zij dagelijks meer dan een derde van de ziekenhuisopnames.

Gisteren ruim 9000 besmettingen in de UK, de verwachting is rond de 60.000 juli/aug.
Per dag? 8)7
  donderdag 17 juni 2021 @ 14:40:33 #125
37149 slashdotter3
Arrow to the knee!
pi_199927055
Phizer en Moderna 88%, AZ (en Janssen) 60%

the Pfizer vaccine showed 88 percent effectiveness against symptomatic disease caused by the Delta variant compared to 93 percent against the Alpha variant. Two doses of AstraZeneca vaccine were 66 percent effective against Alpha but only 60 percent against Delta. But with just single dose of either of the two vaccines, the vaccine effectiveness was only 51 percent against the Alpha variant compared to 33 percent against Delta. This effectiveness falls below the 50 percent efficacy threshold the FDA had set for designing safe COVID-19 vaccines; in which a vaccine should prevent at least half of the vaccinated people from getting COVID-19 symptoms.

=======================================
https://www.reddit.com/r/(...)eres_why_its_on_the/

The Delta variant is serious. Here’s why it's on the rise. The virus variant that caused infections to spike in the U.K. is now spreading in the U.S., and experts are very worried. BYSANJAY MISHRA PUBLISHED JUNE 16, 2021 9 MIN READ

With vaccination rates slowing in the United States, and other countries struggling to secure vaccines, public health experts have growing concerns that the so-called Delta coronavirus variant, first identified in India in March, could trigger dramatic rises in cases and deaths in the U.S. and the world.

The Delta variant already accounts for 18 percent of cases in Colorado, Montana, North Dakota, South Dakota, Utah, and Wyoming, and about six percent of cases nationwide. It has already spread to more than 70 countriesand is now the most dominant variant in India, the United Kingdom, and Singapore. Last week, Delta caused more than 90 percent of the new COVID-19 cases in the U.K., leading to a 65 percent bump in new infections since May 1. On Monday, to curb Delta’s spread, the U.K. government decided to postpone “freedom day,” which would mark the end of public health restrictions.

The Delta variant is 60 percent more transmissible than the Alpha variant—first identified in the U.K.—which in turn was about 50 percent more transmissible than the ancestral Wuhan strain. “It’s a super spreader variant, that is worrisome,” says Eric Topol, founder and director of the Scripps Research Translational Institute. It has features that enable escape from the immune system and is perhaps more evasive than the Beta variant (B.1.351) first identified in South Africa, which was the worst until now, says Topol. “Plus, it has the highest transmissibility of anything we've seen so far. It's a very bad combination.”

Dismayed by the trajectory of Delta in the U.K., Anthony Fauci, head of the National Institute of Allergy and Infectious Diseases, warned President Joe Biden last week, “we cannot let that happen in the United States.”

The President echoed those sentiments, tweeting “Folks, the Delta variant—a highly infectious COVID-19 strain—is spreading rapidly among young people between 12 and 20 years old in the U.K. If you’re young and haven’t gotten your shot yet, it really is time.” A complete dose of a COVID-19 vaccine is still effective at preventing serious COVID-19 stemming from Delta infection.

Why is the Delta variant so scary? Freely circulating viruses, especially coronaviruses and influenza viruses, which encode their genetic instructions using the molecule RNA, mutate frequently and randomly due to copying errors introduced as they replicate in their human host cells. Some mutations enable the virus to evade antibodies; some enhance its ability to infect a cell; others go unnoticed since they yield no benefits or can even weaken it.

The key to Delta’s success is the collection of mutations the variant has accumulated in the spike protein, which covers SARS-CoV-2 and gives the virus its signature crown-like appearance. These mutations have changed the spike, and, as a result, some of the existing antibodies may not bind as tightly or as often, explains Markus Hoffmann, an infectious disease biologist at the Leibniz Institute for Primate Research in Germany. Hoffman has shown that Delta’s closely related Kappa variant evades antibodies that were generated through previous infection and vaccination; it also resists synthetically produced antibody therapies like bamlanivimab.

The Delta variant has mutations on the spike protein that alter how it interacts with the ACE2 receptor protein, which is found on the surface of lung and other human cells and is the portal to invade the cell. The mutation at location 452 of the spike protein, which is also present in some of the California variants, appears to make the virus more transmissible and helps it spread through the population, explains Mehul Suthar, an immunologist at the Emory Vaccine Center.

If a mutation gives a virus a fitness or reproductive advantage, that mutation tends to evolve independently around the world. Delta, its closely related variants, and the highly contagious Alpha variant all carry a mutation at position 681 of the spike protein, which is thought to be an evolutionary game changer that also makes it easier for SARS-CoV-2 to invade the host cell and spread. This mutation is fast becoming common in COVID-19 viruses around the globe.

In addition to these mutations a recent study, not peer reviewed, shows a variation at position 478 on Delta’s spike that enables the virus to escape from weak neutralizing antibodies. This mutation has also become increasingly common in SARS-CoV-2 variants in the U.S., Mexico, and Europe since early 2021.

“When you have all of these mutations, then you start seeing a difference in infectivity (of the virus),” says Ravindra Gupta, a professor of clinical microbiology at the University of Cambridge, who has shown in an unpublished studyhow these variants can have a greater potential to cause disease.

Vaccines less effective against this super spreader The data from India and the U.K. show that Delta has emerged as the dominant variant in those countries within four to six weeks. That indicates Delta is more transmissible and infectious than the previous variants. There is emerging evidence that it can also cause more severe disease. For example, in Scotland it caused about twice as many hospitalizations than the Alpha variant, which already caused more severe illness than the original SARS-CoV-2.

“This combination of high transmissibility, high severity, and escape from vaccines makes Delta a very, very dangerous variant,” says Deepti Gurdasani, a clinical epidemiologist at Queen Mary University of London. Once Delta enters a country, it is going to spread rapidly. “It's going to be quite hard to contain, and very likely will become the dominant variant in a matter of weeks. It could change the trajectory of the global pandemic.”

While vaccines are still effective against severe disease and hospitalization caused by the Alpha and Beta variants, they offer less protection against Delta. People who were vaccinated with one or two doses of the Pfizer vaccine produced lower levels of antibodies capable of neutralizing the Delta variant compared with the levels generated against Alpha and Beta. In the U.K., 31 percent of all confirmed Delta variant patients who needed emergency care had received at least one vaccine dose.

Similarly, a study under review revealed that after both doses, the Pfizer vaccine showed 88 percent effectiveness against symptomatic disease caused by the Delta variant compared to 93 percent against the Alpha variant. Two doses of AstraZeneca vaccine were 66 percent effective against Alpha but only 60 percent against Delta. But with just single dose of either of the two vaccines, the vaccine effectiveness was only 51 percent against the Alpha variant compared to 33 percent against Delta. This effectiveness falls below the 50 percent efficacy threshold the FDA had set for designing safe COVID-19 vaccines; in which a vaccine should prevent at least half of the vaccinated people from getting COVID-19 symptoms.

In other studies still awaiting peer review, researchers report that Delta was responsible for most breakthrough infections—which occur after full vaccination—in India leading to a cluster of such cases among fully vaccinatedhealthcare workers.

There are many vaccine candidates being rolled out around the world and since there are no agreed international efficacy standards, each vaccine might offer a varying degree of protection against new variants. “We need more information about the performance of some of the more widely available vaccines in other parts of the world,” says physician and virologist Benjamin Pinsky of Stanford University School of Medicine. “I think folks need to make sure they get vaccinated. And until they are fully vaccinated, continuing with public health intervention is very important,” he says.

A vaccine alone only slows down the progression of a contagious disease by increasing the herd immunity. Until that point, preventive measures such as social distancing and masking are proven strategies for curbing the spread of the virus.

With just 44 percent of the U.S. population fully vaccinated, the majority of people are still vulnerable. Relaxing public health restrictions and declaring victory prematurely could provide an opportunity for the Delta variant to surge–particularly in the fall.

A study, not yet published, suggests the possibility of seasonal variations in COVID-19 incidence based on analyses from a full year of the pandemic in Europe and Israel. While the virus’s seasonal trends may not be clear yet, says Topol, we do know that when people spend more time indoors with poor ventilation and low humidity the virus spreads more rapidly.

What is happening in the U.K. could occur in many places worldwide. “We should keep social distancing after vaccination, because there will always be possibilities of breakthrough infection because vaccines can still be imperfect against emerging variants,” says Kei Sato,a virologist at the University of Tokyo, Japan, who has been studying the effect of mutations on the transmission of Delta and other emerging variants.

“The more variants like this spread, especially in unvaccinated individuals, the more these viruses mutate and eventually pick up mutations that allow for more efficient antibody escape. This could, in theory, make the current vaccines even less effective against these variants.” Suthar cautions.

If we don’t take Delta seriously, “there will be a further wave in the U.S. We can already see the fall in cases has plateaued,” cautions Gupta. Topol agrees that if we ignore this variant “we’ll have a significant rise in cases in vulnerable areas, more hospitalization, and the pandemic here will last longer.”

[ Bericht 0% gewijzigd door slashdotter3 op 17-06-2021 14:50:27 ]
  donderdag 17 juni 2021 @ 14:41:42 #126
9001 Gunner
#teamkroegenlos
pi_199927087
LUID DE NOODKLOK

(weer dat gezeur over percentages bareuh)

maar wel allemaal het vliegtuig weer in he en die shit meenemen.
Where law ends, tyrrany begins.
pi_199927113
Toch weer goed van Hugo.
pi_199927114
quote:
0s.gif Op donderdag 17 juni 2021 14:36 schreef chratnox het volgende:

Zijn die mensen volledig gevaccineerd of hebben ze alleen een enkele gehad?
Volledig gevaccineerden.
pi_199927129
quote:
0s.gif Op donderdag 17 juni 2021 14:43 schreef Za het volgende:

[..]

Volledig gevaccineerden.
bron?
  donderdag 17 juni 2021 @ 14:44:19 #130
94451 SillyWalks
Ministry of Silly Walks
pi_199927137
quote:
0s.gif Op donderdag 17 juni 2021 14:36 schreef chratnox het volgende:

[..]

Meer dan een derde van de ziekenhuisopnames van mensen die gevaccineerd zijn? Dat is nogal veel.

Zijn die mensen volledig gevaccineerd of hebben ze alleen een enkele gehad?
Bijna allemaal slechte één enkele vaccinatie Oxford/AstraZeneca, waarvan we weten dat één prik niet zoveel doet.
Minister: lt's not particularly silly, is it? I mean, the right leg isn't silly at all and the left leg merely does a forward aerial half turn every alternate step.
Mr Pudey: Yes, but I think that with Government backing I could make it very silly.
pi_199927157
quote:
0s.gif Op donderdag 17 juni 2021 14:39 schreef WheeledWarrior het volgende:

Per dag? 8)7
Ja volgens publicaties van de UK Govt.
pi_199927162
quote:
0s.gif Op donderdag 17 juni 2021 14:43 schreef Za het volgende:

[..]

Volledig gevaccineerden.
Niet jokken he...
pi_199927189
quote:
0s.gif Op donderdag 17 juni 2021 14:43 schreef Za het volgende:

[..]

Volledig gevaccineerden.
Inclusief 1e booster-shot?
pi_199927193
quote:
0s.gif Op donderdag 17 juni 2021 14:43 schreef Za het volgende:

[..]

Volledig gevaccineerden.
Dat klinkt niet heel logisch. Tijdje terug hadden ze 120 ziekenhuisopnames ofzo waar een handjevol gevaccineerd waren waar het gros maar één vaccinatie had.

Als meer dan 30% van de ziekenhuisopnames mensen die volledig gevaccineerd zijn inhoudt zou dit wel groter nieuws zijn.

[ Bericht 2% gewijzigd door #ANONIEM op 17-06-2021 14:47:33 ]
pi_199927218
quote:
0s.gif Op donderdag 17 juni 2021 14:43 schreef Za het volgende:

[..]

Volledig gevaccineerden.
Je blijft ook gewoon glashard liegen en feiten verdraaien naast je constante gegoochel met cijfers en deze weergeven zoals het jou uitkomt.
  donderdag 17 juni 2021 @ 14:48:47 #137
94451 SillyWalks
Ministry of Silly Walks
pi_199927221
quote:
0s.gif Op donderdag 17 juni 2021 14:34 schreef Za het volgende:

[..]

Inmiddels raken steeds meer gevaccineerden besmet, en vertegenwoordigen zij dagelijks meer dan een derde van de ziekenhuisopnames.
Heb je hier een bron van?
Minister: lt's not particularly silly, is it? I mean, the right leg isn't silly at all and the left leg merely does a forward aerial half turn every alternate step.
Mr Pudey: Yes, but I think that with Government backing I could make it very silly.
pi_199927249
quote:
0s.gif Op donderdag 17 juni 2021 14:47 schreef chratnox het volgende:

Dat klinkt niet heel logisch. Tijdje terug hadden ze 120 ziekenhuisopnames ofzo waar een handjevol gevaccineerd waren waar het gros maar één vaccinatie had.

Als meer dan 30% van de ziekenhuisopnames mensen die volledig gevaccineerd zijn inhoudt zou dit wel groter nieuws zijn.


https://www.google.com/ur(...)dU7vQZJ6OM0mQdRU-NE_
pi_199927259
quote:
0s.gif Op donderdag 17 juni 2021 14:48 schreef -0- het volgende:

Je blijft ook gewoon glashard liegen en feiten verdraaien naast je constante gegoochel met cijfers en deze weergeven zoals het jou uitkomt.
Bron is UK Government.
pi_199927265
quote:
0s.gif Op donderdag 17 juni 2021 14:48 schreef Za het volgende:

[..]

Er zijn talloze artikelen, maar bv deze:
https://metro.co.uk/2021/(...)tter_impression=true
Met Corona of door Corona? :+
  donderdag 17 juni 2021 @ 14:53:26 #141
94451 SillyWalks
Ministry of Silly Walks
pi_199927278
quote:
Dat is een 'modelling' ivm een 'roadmap'. Daar wordt niet gesproken over echte cijfers...
Minister: lt's not particularly silly, is it? I mean, the right leg isn't silly at all and the left leg merely does a forward aerial half turn every alternate step.
Mr Pudey: Yes, but I think that with Government backing I could make it very silly.
pi_199927284
Ik hoorde net op de BBC dat in China de deskundigen die Delta-variant als een grotere bedreiging zien dan als de initiële Covid-uitbraak.
blablablabla
  donderdag 17 juni 2021 @ 14:54:00 #143
94451 SillyWalks
Ministry of Silly Walks
pi_199927291
quote:
0s.gif Op donderdag 17 juni 2021 14:48 schreef Za het volgende:

[..]

Er zijn talloze artikelen, maar bv deze:
https://metro.co.uk/2021/(...)tter_impression=true
Dat is één journalist, zonder bron, en ze heeft het over doden, niet over ziekenhuisopnames.
Minister: lt's not particularly silly, is it? I mean, the right leg isn't silly at all and the left leg merely does a forward aerial half turn every alternate step.
Mr Pudey: Yes, but I think that with Government backing I could make it very silly.
pi_199927295
Present.
pi_199927298
quote:
0s.gif Op donderdag 17 juni 2021 14:53 schreef Elan het volgende:
Ik hoorde net op de BBC dat in China de deskundigen die Delta-variant als een grotere bedreiging zien dan als de initiële Covid-uitbraak.
Ik ben TEGEN India.
pi_199927299
quote:
0s.gif Op donderdag 17 juni 2021 14:48 schreef Za het volgende:

[..]

Er zijn talloze artikelen, maar bv deze:
https://metro.co.uk/2021/(...)tter_impression=true
Dit is wat daar staat:
quote:
Almost one third of people in the UK who have so far died from the Indian variant had received both their vaccinations.
Oftewel, bijna een derde van de mensen die overleden zijn van de Delta variant hebben beide vaccinaties gehad. Even los van 't feit dat die groep erg klein is is 't iets heel anders dan meer dan een derde van de ziekenhuisopnames

Uiteraard kun je dit bericht ook omdraaien. Hoewel de Delta variant zo aanwezig is is er maar een kleine groep mensen overleden, wat een teken is dat vaccinaties goed werken. Sterker nog, 12 mensen die overleden zijn terwijl ze beide vaccinaties hebben gehad kan eerder een immuundefect of iets anders inhouden, anders hadden die cijfers wel hoger geweest.
pi_199927333
quote:
0s.gif Op donderdag 17 juni 2021 14:47 schreef chratnox het volgende:

Dat klinkt niet heel logisch. Tijdje terug hadden ze 120 ziekenhuisopnames ofzo waar een handjevol gevaccineerd waren waar het gros maar één vaccinatie had.
Er zijn gewoon steeds meer volledig gevaccineerden, in de kwetsbare groepen 90% of meer.
Die mensen hebben gecompromitteerde immuunsystemen, dus logisch dat zij niet kunnen rekenen op optimale bescherming van vaccins, met name bij varianten zoals heden in de UK.
pi_199927337
quote:
Ok, dit is wel cruciale context.

Hoe ouder je wordt hoe slechter je immuunsysteem werkt, dat is wel een belangrijk punt om mee te nemen in het hele verhaal.
pi_199927338
quote:
0s.gif Op donderdag 17 juni 2021 14:54 schreef Zipportal het volgende:

[..]

Ik ben TEGEN India.
Die 2kBritten hadden India gewoon op de rode lijst moeten zetten qua vliegverkeer, zoals eigenlijk de hele regio.

Echt helemaal klaar met dit griepje.
blablablabla
  donderdag 17 juni 2021 @ 14:57:27 #150
3542 Gia
User under construction
pi_199927354
quote:
0s.gif Op donderdag 17 juni 2021 14:53 schreef Elan het volgende:
Ik hoorde net op de BBC dat in China de deskundigen die Delta-variant als een grotere bedreiging zien dan als de initiële Covid-uitbraak.
Koekje van eigen deeg.
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