Hier een verslag over tinnitus als bijwerking:quote:Op woensdag 25 augustus 2021 14:00 schreef naaktslakkenverkrachter het volgende:
Ik open dit topic maar eens, gezien er gek genoeg nog geen topic over is (alsof het niet voorkomt, wat ik niet geloof).
Er is een groeiende groep mensen die (langdurige) klachten rapporteren na de vaccinatie. Er is nu zelfs een site voor:
https://www.c19vaxreactions.com/
Ook hier maar liefst 471 pagina's aan klachten:
https://vestibular.org/fo(...)accine-side-effects/
En hier:
https://www.tinnitustalk.(...)relevance&c[node]=11
Duizeligheid, oorsuizen, tintelingen, uitval van ledematen, hersenschade... Van alles wordt gerapporteerd. Wat zijn jullie ervaringen?
Als dat zo was dan hadden we dat nu delta dominant is allang gemerkt. Ook zouden alle mensen die met de originele strain besmet zijn geweest dan dat probleem ook hebben gehad.quote:Op zaterdag 25 september 2021 00:58 schreef Probably_on_pcp het volgende:
Mogelijke bijwerking zou ADE kunnen zijn:
Infection-enhancing anti-SARS-CoV-2 antibodies recognize both the original Wuhan/D614G strain and Delta variants. A potential risk for mass vaccination?
Highlights
-Infection-enhancing antibodies have been detected in symptomatic Covid-19.
-Antibody dependent enhancement (ADE) is a potential concern for vaccines.
-Enhancing antibodies recognize both the Wuhan strain and delta variants.
-ADE of delta variants is a potential risk for current vaccines.
-Vaccine formulations lacking ADE epitope are suggested.
Abstract
Antibody dependent enhancement (ADE) of infection is a safety concern for vaccine strategies. In a recent publication, Li et al. (Cell 184 :4203–4219, 2021) have reported that infection-enhancing antibodies directed against the N-terminal domain (NTD) of the SARS-CoV-2 spike protein facilitate virus infection in vitro, but not in vivo.
However, this study was performed with the original Wuhan/D614G strain. Since the Covid-19 pandemic is now dominated with Delta variants, we analyzed the interaction of facilitating antibodies with the NTD of these variants. Using molecular modeling approaches, we show that enhancing antibodies have a higher affinity for Delta variants than for Wuhan/D614G NTDs.
We show that enhancing antibodies reinforce the binding of the spike trimer to the host cell membrane by clamping the NTD to lipid raft microdomains. This stabilizing mechanism may facilitate the conformational change that induces the demasking of the receptor binding domain. As the NTD is also targeted by neutralizing antibodies, our data suggest that the balance between neutralizing and facilitating antibodies in vaccinated individuals is in favor of neutralization for the original Wuhan/D614G strain.
However, in the case of the Delta variant, neutralizing antibodies have a decreased affinity for the spike protein, whereas facilitating antibodies display a strikingly increased affinity. Thus, ADE may be a concern for people receiving vaccines based on the original Wuhan strain spike sequence (either mRNA or viral vectors). Under these circumstances, second generation vaccines with spike protein formulations lacking structurally-conserved ADE-related epitopes should be considered.
https://www.journalofinfection.com/article/S0163-4453(21)00392-3/fulltext#relatedArticles
Natuurlijk wel eerst de disclaimer goed lezen:quote:Op woensdag 6 oktober 2021 12:33 schreef Probably_on_pcp het volgende:
VigiAccess was launched by the World Health Organization (WHO) in 2015 to provide public access to information in VigiBase, the WHO global database of reported potential side effects of medicinal products.
Side effects – known technically as adverse drug reactions (ADRs) and adverse events following immunization (AEFIs) – are reported by national pharmacovigilance centres or national drug regulatory authorities that are members of the WHO Programme for International Drug Monitoring (PIDM). WHO PIDM was created in 1968 to ensure the safer and more effective use of medicinal products.
http://vigiaccess.org/
Typ in: Covid-19 vaccine en ga dan naar ADR (Adverse Drug Reactions). Dit is het resultaat:
.......
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