Met mijn huid gaat het weer redelijk goed sinds ik gestopt bent, 1,5 maand geleden. Misschien dat mijn huid moest wennen of zo. Heb nu 1 miniscuul rood plekje in een week gehad, waar ik niet eens zeker van ben of het een puistje of iets in die richting is. Ik heb gisteren ook een interessant PDF'je gevonden, met ondere andere de volgende dingen erin:
Patients treated with Accutane often relapse (30-50%) and need retreatment (especially women, patients under 20, those with severe acne). Response rate is 95%.
Ik ben dus onder de 20, de rest voldoe ik niet aan. Maar ik vind een relapse rate van 50% dus toch tegenvallen.
En de rest:
1. Accutane is the only drug that works on all four pathogenic mechanisms of acne: abnormal keratinization, increased sebum production, P. acne and inflammation. The other agents work on one or two.
2. A family history of cystic acne is highly predictive of the need for Accutane.
3. Scarring of the skin due to acne suggests that Accutane is indicated.
4. Patients treated with Accutane often relapse (30-50%) and need retreatment (especially women, patients under 20, those with severe acne). Response rate is 95%.
5. Aim for total dose 120mg/kg –can get there with any treatment regime you wish.
6. Teratogen, so use 2 forms of effective contraception (call 1-887-882-2263 ext. 101 to get Pregnancy Prevention Program).
7. Ask about family history of depression and monitor carefully. However incidence of depression is not higher than the general population.
8. Differin topical is better for sensitive skin.
9. The combination of topical antibodies/benzoyl peroxide decreases the risk of antibiotic resistance in P. acne.
10. Diane-35, Tricyclen can decrease acne in women needing contraception.
11. Oral minocin can cause a hypersensitivity syndrome at 2-4 weeks in (fever, rash, abnormal LFT, renal and pulmonary effects). It can also cause pseudotumor cerebri, lupus, and single organ dysfunction.
Bron:
CHR – Department of Family Medicine Rounds - April 5, 2001
Dermatology Update
Dr. Stewart Adam
[ Bericht 2% gewijzigd door IntelliEye op 31-10-2005 11:57:21 ]